Peptide YachikhalidweKaphatikizidweUtumiki
Hangzhou Go Top Peptide Biotech , yomwe idakhazikitsidwa mu 2014, ndi National High-Tech Enterpriseokhazikika pa kafukufuku, chitukuko ndi kupanga ma peptides ndi zotumphukira zina.
Kampaniyopeptide Research Centerpakadali pano ili ku Qiantang Districtof Hangzhou, kuphimba kudera la mamita lalikulu oposa 3,000.Thekampani's fakitale ili pa No.24, Haitian Road, Shangyu District, mzinda wa Shaoxing, m'chigawo cha Zhejiang.Palinso zomera ziwiri za mgwirizano, imodzi ndi yamalonda peptide GMP kupanga zili muAnji County, Zhejiang Province, imodzi ndi ya API yaing'ono ya molekyulu yomwe ili mkatiYuncheng mzinda wa Shanxi Province.Timasandukabizinesi yaukadaulo wapamwamba kwambiri, kuphatikiza kafukufuku, kukwera koyendetsa, malonda ndi malonda padziko lonse lapansi.
Kampaniyo yachitachatha100antchito,ndipo alianatukuka kuposa40 okhwima mankhwalapeptides,kuposa10 ma patent opangaaloledwa.Tiye pachaka mphamvu yopangais mpaka100 kilograms, chiwerengero cha peptides mwambo ali kufika pamwamba pa 20,000.Titha kupereka ma peptide oyimitsa kamodzi kuyambira kafukufuku(mg) mpaka malonda (KGs).
Mndandanda Wosintha wa Peptide
N-ma terminal zosintha
| {N-Me-Ala} | {N-Me-Asp} | {N-Me-Glu} | {N-Me-Ile} |
| {N-Me-Leu} | {N-Me-Met} | {N-Me-Nle} | {N-Me-Nva} |
| {N-Me-Phe} | {N-Me-Ser} | {N-Me-Thr} | {N-Me-Tyr} |
| {N-Me-Val} | {Sar} | N-Me-Arg | N-Me-Asn |
| N-Me-beta-Ala | N-Me-Gln | N-Me-Lys | N-Me-Trp |
C-ma terminal zosintha
| {Mlatho wa Mono Disulfide} | {Mlatho wa Double Disulfide} | {Mlatho wa Triple Disulfide} |
| {Mlatho wa Disulfide mwachisawawa} | {Same Seq.Mlatho wa Inter-Disulfide} | {Mlatho wosiyana wa Inter-Disulfide} |
| {Amide cyclic (mapeto)} | {Amide cyclic (Side chain)} | {Orn side chain Amide cyclic} |
| {Thioester cyclic} | {lactone cyclic} | {Sec cyclic} |
Zachilendo amino zidulo
| {2-Aze} | {3-Aze} | {5,5-Dime-Pro} |
| {5-ASA} | {ABU} | {Ac-Ls} |
| {Ayib} | {Beta-Asp} | {Bpa} |
| {Cha} | {Chg} | {Cit} |
| {Cpg} | {Cs(Acm)} | {Cys(Bzl)} |
Isotope zotchedwa peptides
| Lys(13C6,15N2) | Ile(13C6,15N) |
| Leu(13C6,15N) | Val(13C5, 15N) |
| Arg(13C6, 15N4) |
Kusintha kwa peptide ya fluorescent/FRET pairs
| Biotin - | Dansyl- | Peptide ya fluorecent yazimitsidwa |
| Biotin-Ahx- | Dansyl-Ahx- | Dabcyl |
| 5-FAM- | Cy3- | Dabcyl / Glu(Edans)-NH2 |
| 5-FAM-Ahx- | Cy5- | Dansyl- |
| FITC- | MCA/DNP | Dansyl-Ahx- |
| FITC-Ahx- | AMC | Edans / Dabcyl |
Peptide Conjugates
| BSA (-COOH ya C terminal | KLH(-NH2 ya N terminal) | OVA(-COOH ya C terminal) |
| BSA Conjugation pa Cys | Kulumikizana kwa KLH pa Cys | OVA(-NH2 ya N terminal) |
| Kulumikizana kwa OVA pa Cys |
Phosphorylation
| {pSer} | {D-pSer} |
| {pTyr} | {D-pTyr} |
| {pThr} | {D-pThr} |
Zosintha zina (PEGylation, Cyclic zosintha, Disulfide Bridges)
| PEGylation | Kusintha kwa cyclic | Milatho ya Disulfide |
| {Mini-PEG1} | Mutu mpaka mchira cyclic | {Mlatho wa Mono Disulfide} |
| {Mini-PEG2} | {Mlatho wa Double Disulfide} | |
| {PEG-11} | {Mlatho wa Triple Disulfide} | |
| {PEG-12} | {Mlatho wa Disulfide mwachisawawa} | |
| ……… | ……… | ……… |