Panthawi ya kaphatikizidwe ka peptide, mchere wina umafunika kuwonjezeredwa.Koma pali mitundu yambiri ya mchere, ndipo mitundu yosiyanasiyana ya mchere imapanga ma peptide osiyanasiyana, ndipo zotsatira zake sizifanana.Chifukwa chake lero timasankha makamaka mtundu woyenera wa mchere wa peptide mu kaphatikizidwe ka peptide.
1. Trifluoroacetate (TFA) : Uwu ndi mchere womwe umagwiritsidwa ntchito kwambiri muzinthu za peptide, koma uyenera kupewedwa muzoyesera zina chifukwa cha biotoxicity ya trifluoroacetate.Mwachitsanzo, kuyesa kwa ma cell.
2. Acetate (AC) : The biotoxicity ya asidi acetic ndi yochepa kwambiri kuposa trifluoroacetic acid, choncho peptides ambiri a mankhwala ndi zodzikongoletsera amagwiritsa ntchito acetate, koma mankhwala ena ali ndi acetate osakhazikika, kotero kukhazikika kwa ndondomekoyi kumafunikanso kuganiziridwa.Acetate idasankhidwa pazoyeserera zambiri zamaselo.
3. Hydrochloric acid (HCL) : Mcherewu sumasankhidwa kawirikawiri, ndipo zotsatizana zina zimagwiritsira ntchito hydrochloric acid pazinthu zapadera.
4. Ammonium salt (NH4 +) : Mcherewu udzakhudza kwambiri kusungunuka ndi kukhazikika kwa mankhwala, ayenera kusankhidwa mwadongosolo.
5. Mchere wa sodium (NA +) : nthawi zambiri umakhudza kukhazikika ndi kusungunuka kwa mankhwala.
6. Pamoicacid: Mcherewu nthawi zambiri umagwiritsidwa ntchito mu mankhwala a peptide kuti apange mankhwala otulutsa nthawi zonse.
7. CitricAcid: Mcherewu umakhala ndi poizoni wochepa kwambiri wa thupi, koma kukonzekera kwake kumakhala kovuta kwambiri, choncho ndondomeko yopangira iyenera kupangidwa motsatizana komanso mosiyana.
8. Salicylicacid: Salicylate ingakhudze kukhazikika kwa zinthu za peptide, choncho sagwiritsidwa ntchito kawirikawiri.
Pamwambapa pali mitundu ingapo ya mchere wa peptide, ndipo tiyeneranso kusankha molingana ndi mikhalidwe ya mchere wosiyanasiyana pakugwiritsa ntchito kwenikweni.
Nthawi yotumiza: Jun-16-2023