Njira ya tripeptide ya njoka ya njoka

Ululu wa njoka tripeptide

Analytical standard, HPLC≥98%

Dzina lachingerezi: (2S) -beta-alanyl-l-prolyl-2, 4-Diamino-n -(phenylmethyl)butanamide acetate

Aliases: (2S) -beta-alanyl-l-prolyl 2, 4-diamino-n -(phenylmethyl) butyricoacetate;(2S) -beta-alanyl-l-prolyl-2, 4-Diamino-N -(phenylmethyl)butanamide acetate;SYN-AKE;njoka-tripeptide;H – beta – Ala – Pro – Dab – NHBzl.2 akhwo;Njoka tr

Nambala ya CAS: 823202-99-9

Fomula ya maselo: C19H29N5O3.2(C2H4O2)

Kulemera kwa molekyulu: 495.58

Chiyambi:

Kutsata: H-β-Ala-Pro-Dab-NH-Bzl

Maonekedwe: ufa woyera

Chiyambi chachidule:

Peptide ya utsi wa njoka kwenikweni ndi peptide yaying'ono yomwe imatsanzira poizoni wa njoka.Si ululu wa njoka, koma mawonekedwe a polypeptide ofanana ndi utsi wa njoka.Ma peptides owopsa a njoka anali othandiza kasanu kuchepetsa mizere yosinthika kuposa Botox, ndipo mayeso a vivo adawonetsa kuti atatha masiku 28 akugwiritsidwa ntchito anali ndi zotsatira zomwe zidachepetsa makwinya ndi 52%

Kuchita bwino:

1. Makwinya ndi oletsa kukalamba

2. Chotsani zotsatira za khungu

3. Zodzikongoletsera za nkhope, khosi ndi manja

4. Chepetsani mawonekedwe a khungu, pangani khungu kukhala loyera, lachifundo komanso losakhwima, sinthani mawonekedwe onse

5. Ikhoza kulowa mu khungu lakuya la nkhope, kusunga khungu, ndi kuchotsa zotsalira zomwe zatsala ndi zaka

6. Sewerani zokometsera ndi zonyowa, kuti khungu likhale lachifundo komanso losalala, lokongola monga kale.

7. Kuthira madzi, kuletsa kukalamba, kuwonetsa nkhope yozungulira yooneka ngati V, kuchepetsa unyamata wa khungu la nkhope.

8. Tetezani khungu ku kupanga melanin

Zotsatira:

Ma dipeptide diaminobutylbenzylamide diacetate/venom-like tripeptide atha kugwiritsidwa ntchito ngati chinthu chothandizira kukonza bwino ndikuchotsa makwinya popumula minofu ya nkhope.Ntchito ya tripeptide imachita chimodzimodzi monga Waglerin1, gulu lotsekereza neuromuscle mu TempleViper venom.Ma tripeptides ngati ululu wa njoka amagwiritsidwa ntchito ku nembanemba ya postsynaptic ndipo ndi otsutsa osinthika a muscular nicotinic acetylcholine receptor (nmAChR).tripeptide yaululu wa njoka yomanga nmAChRεsubunit kuteteza kuphatikiza kwa acetylcholine ndi wowonjezera cholandilira, chifukwa mu wowonjezera cholandirira kutsekedwa, mu chatsekedwa zinthu sodium ion sangathe kugwiritsidwa ntchito, sangathe depolarization, mitsempha excitation kufala chipika, mpumulo minofu.