Kodi conotoxin ndi chiyani?Kodi mungachotse makwinya?

conotoxin (conopeptide, kapena CTX), chodyera cha ma peptides ambiri a monotoxic otulutsidwa ndi machubu a poizoni ndi tiziwalo timene timatulutsa a Marine gastropod invertebrate Conus (Conus).Zigawo zazikuluzikulu ndi mankhwala a polypeptide omwe ali odziwika kwambiri kumayendedwe osiyanasiyana a calcium ndi zolandilira zamanjenje.Poizoni wa nkhono iliyonse imakhala ndi ma peptides 50 mpaka 200 omwe amagwira ntchito.Mitundu yosiyanasiyana ya nkhono zamtundu zimakhala ndi ma peptides osiyanasiyana, ngakhale nkhono zomwezo chifukwa cha zigawo zosiyanasiyana, zigawo zake za poizoni zimatha kukhala zosiyana, makamaka pakhoza kukhala ma peptides oposa 50 zikwi zosiyana zogwira ntchito mu poizoni wa nkhono.Conotoxin nthawi zambiri imapangidwa ndi zotsalira za 10 ~ 40, zomwe zili ndi magulu awiri kapena atatu a mgwirizano wa disulfide, umapezeka kuti ndi nambala yaying'ono kwambiri ya nucleic acid ya biological neurotoxic peptide, ndiyenso kachulukidwe kakang'ono ka disulfide chomangira peptide yaying'ono, ingagwiritsidwe ntchito pamitundu yonse. njira za calcium ndi mitundu yolandirira ndi subtypes.

Zotsatira za conotoxin pa makwinya ndi awa:

Conotoxin, ndi banja la conotoxin, ndi mtundu wa zowonjezera zotsutsana ndi ukalamba za mbali, izi ndichifukwa choti zimatha kuchepetsa kuya kwa mizere yabwino, kuchepetsa kulimba kwa khungu, kukhala wopepuka komanso zotanuka, kuzimiririka mizere yabwino, kenako kupeza aliyense. wokondedwa.Imatchedwa "Nyenyezi yotsutsa kukalamba."

Conotoxin imatha kulepheretsa kupanga mizere yabwino kumaso, kumapangitsa kumasuka kwa khungu, kumapangitsa kuti khungu likhale lolimba, kumapangitsa khungu kukhala labwino komanso kuya kwa mizere yabwino.Zimathandiza kuchepetsa kutupa kwa khungu, kulola kuti khungu likonzenso kusungunuka kwake komanso kusintha khungu.

Conotoxin yakhala imodzi mwa njira zomwe zimagwiritsidwa ntchito kwambiri poletsa kukalamba chifukwa chakuchita bwino kwambiri poletsa kukalamba.Ndi njira zapadera, conotoxin imatha kuyikidwa pakhungu la nkhope kuti ipangike bwino.

Conotoxin ngati mtundu wa anti-aging agent, imakhala ndi mphamvu yoletsa kukalamba, kotero imatha kupindula kwambiri kukonza khungu, kuchotsa makwinya, kupangitsa khungu kukhala lokongola kwambiri lachinyamata.