Peptide chain synthesis yakhala ikugwiritsidwa ntchito kwambiri m'magawo ambiri, makamaka pakupanga mankhwala, kafukufuku wazachilengedwe komanso sayansi yazachilengedwe.Ma peptides aatali osiyanasiyana komanso amatsatizana amatha kupangidwa kudzera pa peptide chain synthesis pokonzekera mankhwala, wonyamula mankhwala, kusanthula kwa mapuloteni, kafukufuku wogwira ntchito ndi zina zotero.Ndiye kodi ma peptides opangidwa ndi otani?Lero, Gutuo Xiaobian akupatsani yankho latsatanetsatane pansipa.
Kodi ma peptides osinthidwa mwamakonda ndi chiyani?Kodi mukudziwa mfundo izi?
Kaphatikizidwe ka peptide chain synthesis ikhoza kutheka powonjezera pang'onopang'ono ma amino acid mamolekyu ku unyolo womwe ulipo wa peptide, ndikupanga zomangira zatsopano za peptide.Chifukwa cha kukula kuchokera kumapeto kwa N kupita ku C peptide unyolo, kotero malangizo a kaphatikizidwe amakhalanso kuchokera kumapeto kwa N mpaka C. Izi ndichifukwa chakuti C terminal ndi N terminal amino acids pakati pa peptide bond mapangidwe ndondomeko, ma amino acid a carboxyl end. (C) ndi amino omwe alipo (N) kumapeto kwa peptide chain reaction, amachititsa mgwirizano watsopano wa peptide.Chifukwa chake, mayendedwe a kaphatikizidwe kuchokera kumapeto kwa N kupita ku C.
Peptide kaphatikizidwe makamaka kulumikiza ma amino asidi mamolekyu kudzera mankhwala njira kupanga ndondomeko ya peptides.Kunena zowona, kaphatikizidwe ka polypeptide unyolo ndikulumikizana ndi ma amino acid mamolekyulu, nawonso, amatha kupangidwa ndi zomangira zamankhwala kuti apange njira ya peptides.Peptide chain synthesis nthawi zambiri imatha kuchitidwa ndi kaphatikizidwe kolimba kapena kaphatikizidwe kamadzimadzi.Mu kaphatikizidwe kolimba, ma amino acid oyambira amamangiriridwa ku zinthu zolimba, kenako unyolo wa peptide umakulitsidwa motsatizana powonjezera pang'onopang'ono kwa ma amino acid.
Pamwambapa pali kapangidwe kakang'ono kuti adziwitse gulu la peptide ndi gawo la chidziwitso chofananira, tinto yolimba imayang'ana pa kaphatikizidwe ka peptide, mawu a protein, kukonzekera kwa antibody, ndi zina zambiri, ikuchita nawo makampani a peptide kwazaka zambiri, mtundu woyamba wazinthu. , landirani unyinji wamakasitomala kuti abwere kudzakambirana.
Nthawi yotumiza: Dec-08-2023