Kodi mphotho ya phossurlation mu ma peptides ndi chiyani?

Phossorytion imakhudza mbali zonse za moyo wa ma cell, ndi ma protein amakhudza mbali zonse zolankhulirana zolankhulirana ndi ntchito ndi njira zama cell. Komabe, phosturent phosphorylation ndi chifukwa chachikulu cha matenda ambiri; Makamaka mapuloteni a Kinases ndi phosmases amatha kuyambitsa matenda ambiri, ndipo matenda a tizilombo tating'onoting'ono komanso tizilombo toyambitsa matenda komanso tizilombo toyambitsa matenda timathandizanso kusintha ma prophorlular a intracellaur.

Phosphorylation wa seriine (Ser), chisokonezo (pampando), ndi tyrosine (tyr) ndi njira yosinthira protein. Amachita nawo machitidwe am'manja ambiri, monga ma proceptor osakira, mayanjano a protein ndi gawo, kutsegula kapena kuletsa ntchito ya cell. Ma phosphates amalipiritsa mlandu (zolipiritsa ziwiri zoyipa pa gulu la phosphate). Chifukwa chake, zowonjezera zawo zimatsata katundu wa mapuloteni, omwe nthawi zambiri amasintha, zomwe zimapangitsa kusintha komwe kumapanga mapuloteni. Gulu la phosphate limachotsedwa, kutengera ma protein abwerera kudziko lapansi loyambirira. Ngati mapuloteni awiri azolowera chikuwonetsa zochitika zosiyanasiyana, phossorylation amatha kuchita ngati kusintha kwa ma protein kuti alamulire ntchito yake.

Mahomoni ambiri amawongolera zomwe zimachitika mu ma enzymes a phosphorlat State of serine (ser) kapena chisokonezo (cha tyr) zotsalira, komanso insulin). Magulu a phosphate a mandino acid amatha kuchotsedwa mwachangu. Chifukwa chake, Serat, Mphoto, ndi Tyr Ntchito ngati mabowo amasinthana ndi ma cele a cell monga kuchuluka kwa kuchuluka kwa zaka.

Zojambula zopanga zimatenga gawo lothandiza kwambiri pophunzira za protein kintate magawo ndi machitidwe. Komabe, pali zinthu zina zomwe zimalepheretsa kapena kuchepetsa kutengera masitima a phosphoptis, monga kulephera kukwaniritsa zokhazokha za kaphatikizidwe ka gawo lokhazikika komanso kusagwirizana ndi nsanja wamba.

Technifform sypide synthedes ndi phosylation Kuzimitsa zinthu ndizomwe zingatheke pokwaniritsa magawo awa posintha kaphatikizidwe kake katete, ndipo papulatiki, ndi mamolekyulu omanga.