Davanetide Wopanga / 211439-12-22-22-22/2 / d

Kaonekeswe

Davanetide ndi peptide wopangidwa ndi ma amino acid, ochokera ku mapuloteni a neuroprotective adnp. Imakhala ndi mitsempha, neurotrophic, komanso katundu wotchinga. Davanetide ndi peptive pipti yokhazikika yomwe imatha kukhazikika mapuloteni a microtumbule mu ma neurotus ndipo imatha kuwoloka chotchinga magazi, chokhoza kuletsa kuphatikizika kwa beta-amylooticity imayambitsa. 

Kulembana

Kubwera: zoyera kuti ukhale wopanda ufa

Kuyera (HPLC): ≥980.0%

Kudetsa kamodzi: ≤2.0%

Zambiri za Acetate (hplc): 5.0% ~ 12.0%

Madzi am'madzi (Karl Fischer): ≤10.0%

Zolemba patsamba: ≥80.0%

Kulongedza ndi kutumiza: kutentha kochepa, kutentha kwa vacuum, molondola kwa mg monga amafunikira.

Momwe mungayitanitse?

1. Lumikizanani nafe mwachindunji pafoni kapena imelo: + 86-13735575465, malonda1@gotopbio.com.

2. Kuyitanitsa pa intaneti. Chonde lembani fomu yapaintaneti.

3. Pereka dzina la peptiti, Cas Ayi kapena kutengera, choyera ndi kusinthana ngati pakufunika, kuchuluka, ndi zina zambiri patangotha maola awiri.

4. Kukhazikitsa kutsatana ndi mgwirizano wogulitsira ndi NDA (zopanda kuwulula) kapena mgwirizano wachinsinsi.

5. Tidzasinthiratu kupita patsogolo kwa nthawi.

6. Pipting Kutumiza ndi Dhl, FedEx kapena ena, ndi HPLC, MS, Coa adzaperekedwa ndi katundu.

7. Ndalama zobwezera zidzatsatiridwa ngati pali kusiyana kulikonse kwa ntchito yathu.

8.

Zogulitsa zonse zimangogwiritsidwa ntchito pofufuza zasayansi,’SARLE yoletsedwa kugwiritsidwa ntchito mwachindunji ndi aliyense pa thupi la munthu.

FAQ：

Kodi mumasungunuka bwanji poizo?

Kusungunuka kwa polypeptide kumadalira makamaka kapangidwe kake, mtundu wa zilembo zosintha, mtundu wosinthika ndi ndende yomaliza. Ngati peptide ikapanda kuthekera m'madzi, ultrasound ingathandize kusungunuka. Chifukwa cha peptide woyambira, tikulimbikitsidwa kusungunuka ndi 10% acetic acid; Kwa acidic mapepu, kusungunuka ndi 10% nh4hco3 kumalimbikitsidwa. Ordic solt imathanso kuwonjezeredwanso kwa inlypeptions. Peptideyo imasungunuka pang'ono kuchepera (E.g., DMSO, DMF, isopropyl mowa, methanol, etc.). Ndikulimbikitsidwa kwambiri kuti peputiyi isungunuke mu solvel sorvent kenako kuwonjezeredwa pang'onopang'ono madzi kapena buffer ina mpaka chidwi chofuna.

Kodi Preptio ndi chiyani?
Ndikofunikira kumvetsetsa kusiyana pakati pa zojambulajambula ndi peptide zolemera (kulemera kwakukulu). Mwambiri, peptide a lyophilized ufa sakhala ma peptides okha, komanso zinthu zina monga madzi, ma sol solmed ndi mapepu, ndi mchere. Kulemera kwathunthu kwa peptide (kulemera kwakukulu) kumatanthauza kulemera kwa zosakanizira zonsezi. Zolemba za Peptide ndi zogwirizana ndi zinthu zomwe sizikuwoneka bwino, masuon ndi madzi, ndipo atachotsa izi, zotsalazo ndi zomwe zili patsamba la Peptide. Zojambulajambula za pa intaneti zimatha kutsimikizika ndi kusanthula kwa nayitrogeni kapena amino acid kuwunika, nthawi zambiri kumawerengera 50-80% ya kulemera kwathunthu. Zolemba za Peptide ndizosiyana ndi chiyero choyambira, chomwe chimatanthauza kuchuluka kwa chiwonetsero cha chiwongola dzanja.

Kodi Ubwino wa Prepridical Peptide ndi uti?
Kukula kwachangu kwa zokambirana zam'madzi zam'madzi kuchokera ku zabwino zake zazikulu:

• Zochita zofunika, zogwirizana kwambiri, kuyanjana kwabwino kwa ma receptor, zoopsa zotsika, ndipo sizikudziwa mosavuta m'thupi;

• Poyerekeza ndi mankhwala opanga mapuloteni, kupatula kwa makasitomala a Peptide, mankhwala opezeka panyanja ali ndi imnogenicity wotsika, amafuna magawo ang'onoang'ono, komanso kukhala ndi ntchito zapamwamba;

• Kusavuta kusinthira ndi kupanga, ndipo kumatha kugawana chifukwa cha njira zopangira.

Ndikufuna peptide wa cyclica, yomwe ili ndi tryptophan, kodi idzakhala oxidid?

Makutidwenation a tryptophan ndi chinthu wamba ku Peptide makutidwe, ndipo ma peptides nthawi zambiri amasambira musanayeretsedwe. Ngati makutidwe otsatsa a tryptophan amapezeka, nthawi yosungayisa ya peputiyi pa HPLC Column isintha, ndipo makutidwewo amatha kuchotsedwa ndikuyeretsa. Kuphatikiza apo, ma peptiddid amapezekanso amatha kupezekanso ndi ms.

Kodi peptide ndi koyenera bwanji?
Puptity Synthesis ayenera kuganizira zinthu monga kutalika, kulipira, komanso hydrophilicity wa peputiyo. Kutalika kwa nthawi yayitali, chiyero ndi zipatso zopangidwa ndi kuchepa kwazinthu, komanso zovuta zoyeretsa komanso mwayi wokhala ndi kaphatikizidwe womwewo udzakhala waukulu. Zachidziwikire, gawo la malo ogwirira ntchito a Polypeptide silingasinthidwe, koma chifukwa cha kaphatikizidwe kosalala kwa polyperide acids ayenera kuwonjezeredwa kumtunda ndikutsika kwa ntchito yomwe imagwiritsidwa ntchito pokonzanso. Ngati polypeptide ndi yochepa kwambiri, pakhozanso kukhala zovuta ndi synthesis, vuto lalikulu ndikuti kuvuta kwa polypeptide kumali ndi ma acid a hydrophobic amino. Peptives pansi pa 15 amino atumiki nthawi zambiri amakhala ndi zokolola komanso zokolola.