Lae102 Vendor / Peptide Synthesis / Ogulitsa Chinese

Lae12 Pakadali pano, Lae12 wawonetsa kuthekera mu mitundu yosangalatsa kuti muwonjezere tsinde ndi kuchepetsa mafuta. Kuphatikiza apo, mukamagwiritsa ntchito cholumikizira ndi agonists, Lae12 amathanso kuchepetsa kuchepa kwa misa yopangidwa ndi agonists to glp1r, ndikupangitsa kuti munthu asamalidwe olemera olemera.

Kulembana

Kubwera: zoyera kuti ukhale wopanda ufa

Kuyera (HPLC): ≥98.0%

Kudetsa Kwake: ≤2.0%

Zambiri za Acetate (HPLC): 5.0%～12.0%

Madzi (Karl Fischer): ≤10.0%

Zolemba patsamba: ≥80.0%

Kulongedza ndi kutumiza: kutentha kochepa, kutentha kwa vacuum, molondola kwa mg monga amafunikira.

FAQ：

Ndi njira iti yabwino kwambiri yofufuzira?

Mwachisawawa, peptide imatha ndi gulu la N-termial Free Amino ndi Gulu la C-Termial Free Carboxyl. Pulogalamu ya Peptide nthawi zambiri imayimira mndandanda wa protein. Kuti tikhale pafupi ndi mapuloteni amayiwo, kumapeto kwa peputiyi nthawi zambiri kumafunikira kutsekedwa, ndiye kuti, ma termial acetylay ndi ma tekidal. Kusintha kumeneku kumapewa kuyambitsa kwa chiwopsezo chowonjezera, komanso kumapangitsa kuti alepheretse kuchitapo kanthu mopupuluma, kotero kuti peputiyo imakhala yokhazikika.

Kodi mumasungunuka bwanji poizo?

Kusungunuka kwa polypeptide kumadalira makamaka kapangidwe kake, mtundu wa zilembo zosintha, mtundu wosinthika ndi ndende yomaliza. Ngati peptide ikapanda kuthekera m'madzi, ultrasound ingathandize kusungunuka. Chifukwa cha peptide woyambira, tikulimbikitsidwa kusungunuka ndi 10% acetic acid; Kwa acidic mapepu, kusungunuka ndi 10% nh4hco3 kumalimbikitsidwa. Ordic solt imathanso kuwonjezeredwanso kwa inlypeptions. Peptideyo imasungunuka pang'ono kuchepera (E.g., DMSO, DMF, isopropyl mowa, methanol, etc.). Ndikulimbikitsidwa kwambiri kuti peputiyi isungunuke mu solvel sorvent kenako kuwonjezeredwa pang'onopang'ono madzi kapena buffer ina mpaka chidwi chofuna.

Kodi peptide ndi koyenera bwanji?
Puptity Synthesis ayenera kuganizira zinthu monga kutalika, kulipira, komanso hydrophilicity wa peputiyo. Kutalika kwa nthawi yayitali, chiyero ndi zipatso zopangidwa ndi kuchepa kwazinthu, komanso zovuta zoyeretsa komanso mwayi wokhala ndi kaphatikizidwe womwewo udzakhala waukulu. Zachidziwikire, gawo la malo ogwirira ntchito a Polypeptide silingasinthidwe, koma chifukwa cha kaphatikizidwe kosalala kwa polyperide acids ayenera kuwonjezeredwa kumtunda ndikutsika kwa ntchito yomwe imagwiritsidwa ntchito pokonzanso. Ngati polypeptide ndi yochepa kwambiri, pakhozanso kukhala zovuta ndi synthesis, vuto lalikulu ndikuti kuvuta kwa polypeptide kumali ndi ma acid a hydrophobic amino. Peptives pansi pa 15 amino atumiki nthawi zambiri amakhala ndi zokolola komanso zokolola.

Kodi ndifunika kusamala ndi chiyani pobweretsa kusintha ma fluorescencence ku ma peptides?
Ndikulimbikitsidwa kuti muwonjezere chinsalu pakati pa peptidide molekyu ndi kusintha kwa fluorescent, komwe kumachepetsa kusintha kwa kusintha kwa mbiya pamtengowo ndikumangiriza ku receptor. Komabe, ngati cholinga cha kusintha kwa fluorescence kuyenera kukwaniritsa mawu anzeru pakati pa kapangidwe kake, mawu oyambira ankeker sakulimbikitsidwa.

Chifukwa chiyani ma peptides ayenera kusinthidwa ndi acetylated acetylated ndi ma tedidal?
Zosintha zoterezi zimatha kupatsa ndalama zowerengera zomwe zili zachikhalidwe.