G-v-l-s-v-v-v-y-k-l-l-v-v-v-v-v-v-v-v

Kaonekeswe

G - v - l - n - v - l - l - l - l - l - l - l - l - l - l - k - l - L - L - L - L - L - L - L - L - L - L - L - L - L - L

Kulembana

Kubwera: zoyera kuti ukhale wopanda ufa

Kuyera (HPLC): ≥98.0%

Kudetsa Kwake: ≤2.0%

Zambiri za Acetate (HPLC): 5.0%～12.0%

Madzi (Karl Fischer): ≤10.0%

Zolemba patsamba: ≥80.0%

Kulongedza ndi kutumiza: kutentha kochepa, kutentha kwa vacuum, molondola kwa mg monga amafunikira.

Momwe mungayitanitse?

1. Lumikizanani nafe mwachindunji pafoni kapena imelo: + 86-13735575465, malonda1@gotopbio.com.

2. Kuyitanitsa pa intaneti. Chonde lembani fomu yapaintaneti.

3. Pereka dzina la peptiti, Cas Ayi kapena kutengera, choyera ndi kusinthana ngati pakufunika, kuchuluka, ndi zina zambiri patangotha maola awiri.

4. Kukhazikitsa kutsatana ndi mgwirizano wogulitsira ndi NDA (zopanda kuwulula) kapena mgwirizano wachinsinsi.

5. Tidzasinthiratu kupita patsogolo kwa nthawi.

6. Pipting Kutumiza ndi Dhl, FedEx kapena ena, ndi HPLC, MS, Coa adzaperekedwa ndi katundu.

7. Ndalama zobwezera zidzatsatiridwa ngati pali kusiyana kulikonse kwa ntchito yathu.

8.

Zogulitsa zonse zimangogwiritsidwa ntchito pofufuza zasayansi,’SARLE yoletsedwa kugwiritsidwa ntchito mwachindunji ndi aliyense pa thupi la munthu.

FAQ：

Kodi ma peptides okhala ndi cys amachepetsedwa?

Ngati peptide sanapezeke kukhala oxidized, sitikuchepetsa ma cys. Onse a polypeptides onse amapezeka kuchokera ku mtundu wopanda pake kuyeretsedwa ndi lyophilized pansi pa PH2, zomwe mwina mwina zimalepheretsa ma okosi a CYJ. Peptides okhala ndi ziphuphu zimayeretsedwa ku Ph2 pokhapokha ngati pali chifukwa china choyeretsera pa Ph6.8. Ngati kuyeretsa kumachitika pa Ph6.8, chinthu choyeretsedwa kuyenera kuthandizidwa ndi acidi nthawi yomweyo kupewa maxianation. Mu gawo lomaliza lolamulira, chifukwa cha ma cys, ngati kukhalapo kwa zolemera za madokotala (2p + h) pamapu a MS, zikuwonetsa kuti kuchepa kwapangidwa. Ngati palibe vuto ndi ms ndi hplc, tidzapereka mwachindunji ndi kutumiza katunduyo popanda kukonzanso kwina. Tiyenera kudziwa kuti peptides okhala ndi ma cys oxidation osakhalitsa nthawi yayitali, ndipo kuchuluka kwa makutidwe ndi peptide motsatizana ndi malo osungira.

Kodi mumawona bwanji ngati peptide imatha?

Timagwiritsa ntchito zomwe Ellman amayesa ngati mapangidwe a mphete ndi athunthu. Ngati mayeso a ellman ndi abwino (achikasu), njira yopanda tanthauzo siyabwino. Ngati zotsatira zoyeserera ndizosalakwika (osati chikasu), machitidwe a mphete adakhala athunthu. Sitipereka lipoti la kuwunika kwa chizindikiritso cha makasitomala athu. Nthawi zambiri, pamakhala mafotokozedwe a mayeso a Ellman mu lipoti la QC.

Ndikufuna peptide wa cyclica, yomwe ili ndi tryptophan, kodi idzakhala oxidid?

Makutidwenation a tryptophan ndi chinthu wamba ku Peptide makutidwe, ndipo ma peptides nthawi zambiri amasambira musanayeretsedwe. Ngati makutidwe otsatsa a tryptophan amapezeka, nthawi yosungayisa ya peputiyi pa HPLC Column isintha, ndipo makutidwewo amatha kuchotsedwa ndikuyeretsa. Kuphatikiza apo, ma peptiddid amapezekanso amatha kupezekanso ndi ms.

Kodi ndikofunikira kuyika kusiyana pakati pa peptide ndi utoto?

Ngati mukuphatikiza mamolekyu akulu (monga utoto) ku peptide, ndibwino kuyika danga pakati pa peptide ndi ligand kuti muchepetse kulowererapo ndi chipinda chokha kapena pokupinda kwa conjugate. Ena safuna nthawi. Mwachitsanzo, pakukulunga kwa mapuloteni, ndizotheka kudziwa momwe kulekanitsirana komwe amino acid ndi pomanga utoto wa fluoressicnt ku tsamba linalake.

Ngati mukufuna kusinthidwa kwa biotin ku n crumnal, muyenera kuyika kusiyana pakati pa biotin ndi peptide motsatizana?

Njira ya Biotin yolembedwa ndi kampani yathu ndikuphatikiza ahx ku Trupdite unyolo, wotsatiridwa ndi biotin. AHX ndi 6-kaboni pazinthu za mpweya zomwe zimalepheretsa peptide ndi biotin.

Kodi mutha kupereka upangiri pa kapangidwe ka phosphony fpumudes?

Kutalika kwa nthawi yowonjezereka, kulimbikitsa kumatsika pang'onopang'ono ku phosphoneted amino acid mpwor. Malangizo a Centusis amachokera ku c terminal ku n cyam. Ndikulimbikitsidwa kuti zotsalira pambuyo pa phosphonet amino acid sayenera kupitirira 10, ndiye kuti, kuchuluka kwa Amino Adidi Acid kuchokera ku Nino Acid kuchokera ku cur terminal sayenera kupitirira 10.

Chifukwa chiyani phokoso la N-Scripoal ndi C-tedidal?

Zosintha izi zimalepheretsa chiwopsezo kuti ziwonongeke ndikulola kuti chopimbira kuti zigwirizane ndi gawo lake la alpha ndi magulu a carboxyl mu protein.