Amani acids amapanga mapuloteni a polyteptide omwe kudzera mwa ma polyteride kudzera munthawi zosintha, kutsatira malamulo ena. Njirayi imaphatikizapo kusintha kwamankhwala komwe amino acid mamolekyu ophatikizidwa ndi mawonekedwe a minofu yam'madzi kudzera m'matumbo am'madzi, kenako ndikupangitsa mapuloteni a polypegeside ndi ntchito zina. Kudzera munthawi yam'madzi, ma bond a Peptide amapangidwa pakati pa amino acid. Gawo lofunikira ichi limapangitsa amino acid kuti alumikizidwe m'njira inayake ndi njira, pokonza zovuta za polypepride yovuta. Pambuyo pazachapa, chiwonetsero cha peptide chopangidwa pakati pa amino acid chitha kufupikitsidwa ngati "-, koma chidziwike kuti sichingafikidwe ngati" -cnho.
1.Condextion Makina ndi Polypeptide Mapangidwe
Amino acid amakhala ndi ma polypeption kudzera mwa kusinthidwa kumachitika. Munjira iyi, amino acid amalumikizidwa ndi zingwe zowoneka bwino kudzera pachabechabe, zomwe zimapangitsa ma polypeption ndi ntchito zina, zomwe mapangidwe a Peptide ndi ofunikira.
2. Kukonzanso njira
Munjira yochepetsetsa ya amino acids, gulu la amino la amino acid molekyulu imagwira ndi gulu la carboxyl acid molekwere. Kudzera munthawi yazachilendo, onse pamodzi amapanga cholumikizira. M'minyewa ya amino, gulu la Amino ndi Carboxyl gulu la amino acid mamolekyu a Acids, omwe amatha kuphatikizidwa hydrogen atomu ndi gulu la hydroxyl kuti apange peptide. matenda ochepetsera matenda.
3.Cycluzation
Panthawi yochenjera ya amino acids, kuwonjezera pa zochitika wamba monga dimbusimiti yopangira, zomwe zimachitika pamtunda zimatha kuchitika. Izi zitha kuchitika mkati mwa intramolecularly kapena intramolecularly, zomwe zimapangitsa kupanga kwa ma cyclic omwe kudzera mwa kuvomerezedwa. Kulumikizana kwa kusungunuka kumatha kupanga zopangidwa ndi mphete, ndipo izi sizimangokhala njira zosiyana koma zimatha kuchitika intramolecularlyly, ndikupanga zida zovuta.
4.Colimenstation Action ndi Polypeptide / protein
Munjira yochepetsetsa ya amino acid, zothandizira zimapangitsa kuti ma polypepside atuluke komanso mapuloteni. Izi sizimangotanthauza kuzungulira kwa ma intermolecular kapena imramolecular komanso kumapangitsanso njira zambiri zamankhwala, ndikugwiritsa ntchito zofunika kwambiri kumvetsetsa kapangidwe ka mapu protein pazinthu zachilengedwe.
Post Nthawi: 2025-12-12