Kuyamba koyamba kwa Etelcalcetri-

Mbiri Komanso Mwachidule

Etelcalcetside, dzina lina limatchedwa AMG416.in Malipoti am'mbuyomu, FMOC-LYYS (NPYS) -Oh, ndi amino acid omwe amagwiritsidwa ntchito. Chifukwa cha mtengo wawo wokwera, kupanga zomangira zodetsa zolimba pagawo lokhazikika ali ndi zinthu zambiri zosavomerezeka monga zovuta zowonjezera komanso zovuta. Chifukwa chake, mtengo wotsika mtengo wa H-LYY-OH amagwiritsidwa ntchito ngati chinthu chopangidwa ndi zinthu zomaliza zopangidwa ndi zomangira zapakatikati. Njira zingapo zosavuta za oxidation zimagwiritsidwa ntchito mu gawo lamadzi kuti mupeze yankho lalikulu la velacap. Zomwe zimachitika sizimangochitika munthawi yokhayokha komanso mwamphamvu kwambiriosungidwa muyezo.

Kugwiritsa ntchito etelcalcetide

Etelcalcetide ndi wothandizila wa buku yemwe wapangidwa ndi matenda a impso (odwala) odwala omwe amalandila hemodialysis, kutumikiridwa kudzera m'mitsempha. Amg416 imamangiriza ndikukhazikitsa ma recium-vomerezedwe ka calmyroid glands, zomwe zimapangitsa kuchepetsedwa kwa parathyroid mahomoni (a PT). Imakhala lonjezo lalikulu ngati mankhwala atsopano pochiza matenda achiwiri hperparathyroidism. FDA yavomereza kwambiri vatimimetic veracelipt yochizira matenda a syperparathyrosissississississississississississississis, akuyika woyamba kuvomerezedwa ndi mankhwalawa zaka pafupifupi 12. Odwala omwe ali ndi vuto lalikulu kwambiri hypeparathyroismsm omwe amapezeka hemodialysis adawonetsa kuti ndi mankhwala a Pth atachiritsa ndizabwino kwambiri kuposa plaralbo.

Zambiri Zoyambira
Dzina la China: Varacitide

Dzina la Chingerezi: Etelcalcetide

Kampani No: GT-F046

Cas: 126278-97-1

Mndandanda: ac- {d-cy} - {d-arg} - {d-arg} - {d-arg} - {d-arg} - {d-arg} - {d-arg} - {d-arg} - {D-ARG} - Disg} - Disg} - Disg} - Disg} - Kuchotsa LyyTide Hydrochloride)

Mawonekedwe a mamolecular: c38h73n21o10s2

Kulemera kwa maselo: 1048.25