Amyloid β-peptide (1-42) (munthu): mphamvu yayikulu yazakudya

    Amyloid β-peptide (1-42) (munthu), kodi Amyloid β-peptide ndi chiyani (1-42) (munthu) (munthu), ndi mapindu ake a Amyloid (1-42).

Amyloid β-peptide (1-42) (munthu) ndi mapuloteni osungiramo zinthu zakale za soya. Poyerekeza ndi mapuloteni a amino acin, amyloid β-peptide (1-42) (munthu) amakhala ndi zosinthika zachilengedwe, osakhala ndi madzi, komanso osakhala ndi mpweya pansi mumikhalidwe. Njira yothetsera vutoli ili ndi mafayilo otsika ndipo sagwirizana mukamatenthedwa.

M'zaka zaposachedwa, kafukufuku wadziko lonse lapansi wazindikira kuti mapuloteni amadziwika kuti mapuloteni ang'onoang'ono a peptzy chimbudzi chitatha chimbudzi, ndipo thupi limatha kuyamwa mosavuta komanso mwachangu kuposa ma amino aulere. Ma Peptides ena ang'onoang'ono sangangoperekera zakudya zokukula ndi chitukuko cha anthu, komanso kukhala ndi ntchito zapadera zachilengedwe, zimatha kuchitira ma hyperlipdia, kutopa kwambiri, komanso kutopa kwambiri.

Chifukwa thupi la munthu limatengera mapuloteni mu mawonekedwe a ma peptides m'malo mongokhala ma amino aulere. Nthawi yomweyo, kapangidwe ka mapuloteni muyezo wa ma peptides aumunthu ndi apamwamba kuposa a amino acid. Pali mitundu 20 ya amino acid, omwe adakhazikitsa ndi kuchuluka kochepa. Komabe, pali mazana a ma peptides mazana amapangidwa kuchokera kuma amino acid, okhala ndi ntchito zosiyanasiyana. Mu moyo wamakono, zakudya sizingakhale ndi mapuloteni kapena amino acid, koma thupi limasowa ma peptides.

Komabe, thupi la munthu liyenera kupeza ma peptides ochokera kunja ma peptides kunja kuti atsimikizire thanzi. Chifukwa cha kuchuluka kwa ma amino acid a matetetein, mapuloteni masauzande ambiri amapangidwa mwachilengedwe. Mamolekyu a soya amasungunuka nthawi zambiri amakhala akulu kwambiri, amakhala ndi masauzande kapena masauzande a ma amino acid. Mamolekyu akulu ngati amenewa sangatengeke mwachindunji ndi thupi la munthu. Chifukwa chake, zinthu wamba zowoneka bwino zimapereka zakudya ndi mphamvu ku thupi koma osatenga nawo mbali kapena kuwongolera zochitika zakuthupi. Ndi chitukuko cha enzyme yamakono, asayansi apeza kuti mamolekyulu a soya amatha kusweka m'magawo ang'onoang'ono kudzera mu njira zamakono zosinthira. Zidutswa zazing'ono zokhala ndi ma acid ochepera 50 amadzitchedwa "Peptides kapena ma peptides athunthu." Kutalika kwake ndi katundu wa mapulogalamu mapuloteni ma pupterides kumasiyana malinga ndi ma molekyulu a soya. Amyloid β-peptide (1-42) (munthu) amasiyanitsidwa ndi zonyamula soya. Kutalika kwawo kumakhala kochepera 50 amino acid, makamaka ma amino acid, ndi ma teptur olemera 3000. Zigawo zazikuluzikulu zimaphatikizapo ma peptides antihyperteric, ma peptides antides, okonda kutopa, ndi zina zambiri. Ambiri mwa ma peptides ambiri amakhala achipembedzo mthupi la munthu, ali ndi zolemera zazing'ono, ndipo zimatha kutengeka mwachindunji. Kamodzi m'thupi, amatha kukhalabe ndi ntchito zachilengedwe ndikuchita mwachindunji thupi la munthu.