Kusintha kwa moyo ndi kusintha kwa miyezo ya moyo, kupezeka kwa matenda a shuga pafupifupi 2 kumakhala kukulira kwakukulu, makamaka pakupanga mankhwala ochepetsa thupi kwathanso, omwe ayendetsa chitukuko cha mafakitale onse. Pakadali pano, mankhwala omwe amapezeka pamsika pamsika amaphatikizapo Tirzepatide, Semaglitdide, Liraglutide, Orlistat, mwa ena. Tsopano, membala watsopano wawonjezera——Orffoglipron.
Orffoglipron adapezeka ndi chugai mankhwalam Kampani ku Japan. Mu 2018, kampaniyo yovomerezeka ku chimphona cha mayiko akunja eli chitukuko chatsopano cha ma molekyulu ang'onoang'ono, omwe alibe peptimu pakamwa kwambiri. Pofika Epulo 2025, Orfggipron adamaliza kuyesedwa kwake. Mosiyana ndi mankhwala osokoneza bongo monga Tirzepatide, Orfggipron ndi mankhwala osamwa pakamwa a peptule, omwe amabweretsa mwayi kwambiri.
Malawi:
IneN Ziwonetsero Zacipatala, Orfggipron Yawonetsa kuchepa kwa thupi komanso kutulutsa kwa shuga magazi, zomwe zingakhale ndi matenda ashuga omwe amachititsa manyazi a glucose ndikusintha mphamvu. Gawo 1 Mayesero azachipatala adapeza kuti kapena zotsatira zake zimakhala ndi zotsatira zofanana ndi gyp-1 ndipo zitha kugwiritsidwa ntchito pochiza kunenepa ndi mtundu wa shuga wa 2. Gawo la gawo lachipatala lomwe lawonetsedwa munthawi ya masabata 36, Orfggipron adapangitsa kuti achepetse thupi 9.4% mpaka 14.7% odwala. Mu gawo la sabata la 40 litangano, Orfggipron chochepetsedwa kwambiri hemoglobin pofika 1.24% mpaka 1.48% odwala, akuwonetsa mphamvu zolimba magazi.
Chidule:
Orffoglipron ndi omwe ali ngati Plucagon-ngati peptide-1 (GLP-1) yokhazikitsidwa ndi American Company Eli Lilly, yomwe imatha kusintha kunenepa kwambiri komanso mtundu wa shuga wa 2.
Zambiri Zoyambira：
NAme: Orfglipron
Cas: 22120-52-3
Ma molecular fomula: c48h48f2n10o5
Kulemera kwa maselo: 882.97
Post Nthawi: 2025-09-08