Chidule chachidule cha tidulutide

Njira ya zochita za tidulutide Gattex (teduglutide)

Teduglutide ndi analogi wachilengedwe wamunthu wa glucagon-ngati peptide-2 (GLP-2), peptide yotulutsidwa ndi ma cell a L m'matumbo a distal.GLP-2 imadziwika kuti imathandizira kutuluka kwa magazi m'matumbo ndi portal ndikuletsa katulutsidwe ka m'mimba.Kwa madigiri a lu peptide ndi peptide receptor 2 glucagon zitsanzo, insulini yofanana ndi kukula kwa maselo a m'matumbo a endocrine, maselo a epithelial a minofu ya minofu, submucosa ndi myenteric maimidwe pakati pa matumbo a m'mimba.Kutsegula kwa ma receptor awa kumapangitsa kutulutsa kwamtundu wamitundu yosiyanasiyana, kuphatikiza insulin-like growth factor (IGF) 1, cell growth factor formation nitrogen oxide ndi cutin cell growth factor (KGF).

Tidulutide, glucagon-ngati peptide 2 (GLP-2) analogue, amachepetsa kutuluka kwa m'mimba ndi metabolism ndikuwongolera kukula, kubereka ndi kuchira kwa maselo am'mimba.Peptide idachulukitsa kuchuluka kwa maselowa, imatha kukulitsa kuyamwa kwamatumbo ang'onoang'ono, kuchepetsa kutsekula m'mimba.Matenda am'mimba mwa akulu amatha kuthandizidwa kuchipatala.Mankhwala wakhala woyamba analimbikitsa mankhwala osowa koma kwambiri ofooka.

Chidule chachidule cha tidulutide

Chemical molecular formula ya tidulutide

Basic magawo

Dzina: c peptide (Teduglutide)

Nambala ya GT-F027

Nambala ya CAS: 197922-42-2

Zotsatira: His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn- Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp

Mapangidwe a maselo: C164H252N44O55S

Kulemera kwa molekyulu: 3752.08248